Curt Sigmund, Pharmacology, 319-335-7604
Sigmund receives NIH grant to study blood vessel health
Sigmund receives NIH grant to study blood vessel health
By: UI Health Care Marketing and Communications | 2016.04.15 | 12:23 pm
Curt Sigmund, Ph.D., professor and DEO of pharmacology at the University of Iowa Carver College of Medicine, has been awarded a four-year, $2.48 million grant from the National Institute of Health (NIH) to study a molecular pathway that appears to protect blood vessels from damage caused by cardiovascular stressors, including high-fat diet and aging.
The pathway involves PPAR gamma, a critical protein in the endothelium, the innermost lining of the blood vessel. The research aims to understand the interaction between PPAR gamma and another protein called retinol binding protein 7 (RBP7), which the researchers think may support the beneficial effects of PPAR gamma in the endothelium.
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