heart disease

Grants Boudreau named Carver Trust Young Investigator

Ryan Boudreau, UI assistant professor of internal medicine, has received a three-year, $438,657 Young Investigator award from the Roy J. Carver Charitable Trust to investigate regulatory mechanisms that control when and where proteins are made within heart cells.

Regents approve request to re-name center in honor of founder

Center renamed the Francois M. Abboud Cardiovascular Research Center
The Board of Regents, State of Iowa, today (Wednesday, Dec. 4) approved a request from the University of Iowa to re-name the UI Cardiovascular Research Center in honor of its founder, Francois Abboud, M.D.

Your finger's pulse holds the key to your heart's health

New technique from UI study uses finger's pulse to measure stiffness in the aorta
A University of Iowa physiologist has a new technique to measure the stiffness of the aorta, a common risk factor for heart disease. The procedure involves measuring the pulse in the finger or on the arm, combined with an individual's age and body mass index. Results are published in the "American Journal of Physiology Heart and Circulatory Physiology."
Close up photo of a hand holding an inhaler for asthma treatment

KGAN TV UI has breakthrough in asthma research

A new finding from researchers at the UI may take asthma treatment to another level, according to Joel Kline, M.D., director of the UI's Asthma Center.

A promising target to treat asthma

University of Iowa team finds enzyme in airway lining cells could hold key for asthma sufferers
A University of Iowa-led team has found a promising, new way to treat asthma: Target an enzyme in airway lining cells. The finding could lead to the development of drugs that block the enzyme, CaMKII, from excessive oxidation, which can trigger asthma attacks.

Molecular hub links obesity, heart disease to high blood pressure

Targeting pathway may lead to better hypertension treatments for at-risk patients
A University of Iowa study identifies a brain protein that acts as a communications hub for blood pressure control, and links cardiovascular disease and obesity to hypertension.

Study finds possible link between diabetes, increased heart attack death risk

Overactive enzyme may be factor
Having diabetes doubles a person’s risk of dying after a heart attack, but the reason for the increased risk is not clear. A new University of Iowa study suggests the link may lie in the over-activation of an important heart enzyme, which leads to death of pacemaker cells in the heart, abnormal heart rhythm, and increased risk of sudden death in diabetic mice following a heart attack.

UI heart and stroke prevention study seeks participants

Adults age 45 and older with elevated triglycerides who have had a stroke, heart attack, chest pain, or heart surgery are invited to participate in a University of Iowa research study on preventing these conditions.

Enzyme triggers heart failure

Inhibiting CaMKII activity could lead to new heart disease therapies
A University of Iowa study shows that CaM kinase II enzyme triggers heart cell death by making the cells’ energy-producing mitochondria leaky. Inhibiting the enzyme in mitochondria protected mice from heart cell death during heart attack and other forms of heart stress. The findings could lead to better therapies for common forms of heart disease.