Department of Internal Medicine
Using a screening method that previously identified a compound in apple peel as a muscle-boosting agent, a team of University of Iowa scientists has now discovered that tomatidine, a compound from green tomatoes, is even more potent for building muscle and protecting against muscle atrophy.
Terry L. Wahls, clinical professor of medicine in the University of Iowa Carver College of Medicine, will talk about her new book, "The Wahls Protocol," at 2 p.m. Saturday, March 15, at the Iowa City Public Library.
University of Iowa Hospital and Clinics is recruiting volunteers to participate in a study to compare the long-term benefits and risks of four widely used diabetes drugs in combination with metformin, the most common first-line medication for treating type 2 diabetes.
Having diabetes doubles a person’s risk of dying after a heart attack, but the reason for the increased risk is not clear. A new University of Iowa study suggests the link may lie in the over-activation of an important heart enzyme, which leads to death of pacemaker cells in the heart, abnormal heart rhythm, and increased risk of sudden death in diabetic mice following a heart attack.
Children who had in-hospital cardiac arrest in 2009, were three times more likely to survive than children who had cardiac arrests in 2000. In addition, among surviving children, the risk of severe brain damage appears to have remained unchanged during this period.
A University of Iowa study shows that CaM kinase II enzyme triggers heart cell death by making the cells’ energy-producing mitochondria leaky. Inhibiting the enzyme in mitochondria protected mice from heart cell death during heart attack and other forms of heart stress. The findings could lead to better therapies for common forms of heart disease.